· Find a comprehensive guide to possible side effects including common and rare side effects when taking Desyrel (Trazodone Hydrochloride) for healthcare ...
** Please do not submit confidential or sensitive information, refill requests, social security
numbers or credit card numbers, as this page is not secure. **
Trazodone was approved for medical use in the United States in 1981.  It is available as a generic medication .  The cost in the United Kingdom for the NHS is about pounds per month as of 2015.  In the United States, the wholesale cost is about USD per month as of 2018.  In 2014 about 26 million prescriptions for the medication were filled in the US. 
Carbamazepine induces CYP3A4. Following co-administration of carbamazepine 400 mg/day with trazodone 100 mg to 300 mg daily, carbamazepine reduced plasma concentrations of trazodone (as well as mCPP) by 76% and 60%, respectively, compared to pre-carbamazepine values.