· Find a comprehensive guide to possible side effects including common and rare side effects when taking Desyrel (Trazodone Hydrochloride) for healthcare ...

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Trazodone was approved for medical use in the United States in 1981. [7] It is available as a generic medication . [7] The cost in the United Kingdom for the NHS is about pounds per month as of 2015. [11] In the United States, the wholesale cost is about USD per month as of 2018. [12] In 2014 about 26 million prescriptions for the medication were filled in the US. [13]

Carbamazepine induces CYP3A4. Following co-administration of carbamazepine 400 mg/day with trazodone 100 mg to 300 mg daily, carbamazepine reduced plasma concentrations of trazodone (as well as mCPP) by 76% and 60%, respectively, compared to pre-carbamazepine values.


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